Vascular complications of sickle cell disease
نویسندگان
چکیده
منابع مشابه
Psychological complications in sickle cell disease.
This review examines the evidence for some of the common psychological complications found across the life span of patients with sickle cell disease (SCD), which are likely to be encountered by haematologists responsible for their medical management. Electronic searches of medical and psychological databases were conducted with a focus on three main areas: psychological coping, quality of life ...
متن کامل[Acute complications in sickle cell disease].
Sickle cell disease is an inherited disease characterised by the presence of an abnormal haemoglobin. Sickle cell disease can be complicated by acute vaso-occlusive crisis, which are the major clinical problem prompting admission to hospital and the major cause of death. It mainly manifests by osteo-articular pain and acute chest syndrome and can be complicated by multi-organ failure. The main ...
متن کاملIntracardiac Thrombosis in Sickle Cell Disease
In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...
متن کاملThe clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease.
Sickle cell disease (SCD) is one of the most common inherited diseases in the world and the patients present notorious clinical heterogeneity. It is known that patients with SCD present activation of the blood coagulation and fibrinolytic systems, especially during vaso-occlusive crises, but also during the steady state of the disease. We determined if the presence of the factor V gene G1691A m...
متن کاملVascular Obstruction in Sickle Cell Disease
Initially, the pathophysiology of sickle cell anemia was attributed to deoxygenation-induced polymerization of a mutant form of hemoglobin, hemoglobin S, as well as sickling of red blood cells that plug blood vessels causing the onset of a painful vasoocclusive crisis. Although hemoglobin S polymerization is central to the pathophysiology of this disease, the initiation of a vasoocclusive episo...
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ژورنال
عنوان ژورنال: Clinical Hemorheology and Microcirculation
سال: 2018
ISSN: 1386-0291,1875-8622
DOI: 10.3233/ch-189008